Page 80 - Fisica In Medicina n° 1/2017

^Äëíê~Åí=jÉÇáÅá= =in 88% of cases, while a complete response was observed in 94% of cases for pre-SABR SUV-max < 5 (p < 0.001, Sensitivity = 88%, Specificity = 94%). A pre-SABR SUV-mean < 3.5 was related to complete response at 6 months after SABR (p 0.03, Sensitivity = 31%, Specificity = 34%, AUC = 0.32). In cases of in-field failure, a pre-SABR SUV-max > 8 was related to a higher absolute value increase of SUV-max at 6 months of follow up comparing to pre-SABR SUV-max < 8 (p 0.005). Delta SUV max 3-6 months was +126% for lesions with in-field progression versus -26% for the remaining (p-value 0.002). Delta SUV-mean 3-6 months was +15% for lesions with in-field progression versus for the remaining metastases (p-value 0.008). Finally, 86% of patients with local failure had distant progression versus only 19% in cases without local failure (p = 0.004).ConclusionAccording to current findings, pre-SABR SUV max and mean seem to predict early response in lung SABR for oligometastases.71