Page 69 - Fisica In Medicina n° 1/2017

^Äëíê~Åí=jÉÇáÅá= =For the O-H, the average values of Dmedian, Dmean and D0.1cc were (1.5 + 3.65) Gy, (1.54 + 3.6) Gy, (2.2 + 4.7) Gy, respectively, while the V1Gy, V2Gy, V5Gy and V10Gy values were (25 + 40) %, (18.9 + 35) %, (8.9 + 25.3) % and (2.1 + 11.8) %, respectively. For the C-H, the average Dmedian, Dmean and D0.1cc were (0.7 + 1.5) Gy, (0.7 + 1.4) Gy, (0.9 + 1.8) Gy, respectively, while the average values of V1Gy, V2Gy, V5Gy and V10Gy were (18 + 35) %, (10.2 + 27.7) %, (2.8 + 15.4) % and (1.4 + 11.6) %, respectively. The differences between O-H and C-H, in terms of received dose, was statistically significant (p=0.03). Moreover, the PTV dimension (>5cc or >6cc) did not influenced the dose of hippocampus (p= 0.06; 0.2, respectively).ConclusionDuring SRT/SRS treatments for BM, hippocampus received a very low dose and its clinical significance seems to be negligible, even if it is still under investigation. However, considering the increasing use of SRS/SRT for multiple BM, including also patients with up to 10 BM, the dose to hippocampus need to be seriously evaluated in the treatment planning.60